Histiocytoses - Overview

Histiocystoses is a category of skin disease that is composed of dysregulation of a type of white blood cell called a histiocyte which is either a macrophage or a Langerhans cell.  The category of Histocytoses is further sub divided into the Non-X Histiocytoses composed of macrophages and the X Histiocytoses composed of Langerhans cells.  The Non-X Histiocytoses include: Juvenile Xanthogranuloma, Benign Cephalic Histiocytosis, Generalized Eruptive Histiocytosis, Xanthoma Disseminatum, Progressive Nodular Histiocytosis, Papular Xanthoma, Hereditary Progressive Mucinous Histiocytosis in Women, Reticulohistiocytosis, Multicentric Reticulohistiocytosis, Indeterminate Cell Histiocytosis, and Sea Blue Histiocytosis.  The X Histiocytoses include: Congenital Self Healing Reticulohistiocytosis and Langerhans Cell Histiocytosis.

 Juvenile Xanthogranuloma Histology (http://dermaamin.com/site/images/histo-pic/t/touton-giant-cell-in-juvenile-xanthogranuloma/touton-giant-cell-in-juvenile-xanthogranuloma1.jpg)

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