Proliferating Cysts are malignant cysts that are fortunately very rare and are infrequently encountered in my The Woodlands dermatology and Conroe dermatology offices. All cyst like lesions that I excise are always examined by a board certified dermatopathologist to ensure they are benign and to evaluate for malignancy such as a Proliferating Cyst mimicking a benign cyst. Proliferating Cysts can arise from either Epithelial Inclusion Cysts or Pilar Cysts. Proliferating Epithelial Inclusion Cysts are more common in men and are most often found in the pelvic/anogenital area. They are usually locally aggressive where they enlarge and invade into normal structures but can metastasize in some cases. Proliferating Pilar Cysts are almost exclusively found on the scalp and back of the neck. They are very large (over 25 cm) nodules and behave similar to squamous cell cancers of the skin. Unlike Proliferating Epithelial Inclusion Cysts, they are much more common in women and are typically seen in patients over age 65. Treatment for Proliferating Cysts is excision with a margin of normal skin.
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