Blistering Diseases – Grover’s Disease

December 30th, 2012

Grover’s Disease, also called Transient Acantholytic Dermatosis, is a blistering skin disease that I encounter occasionally in both my The Woodlands dermatology and Conroe dermatology offices.  Grover’s disease is most commonly seen in men over age 50.  Clinically, very fragile vesicles (blisters) appear on the chest, upper abdomen, and upper back and quickly rupture resulting in small red crusted lesions.  Many patients describe the symptoms as very itchy but without any pain.  Typically, heat and sweating can exacerbate the condition.  Grover’s disease is also common in patients on bed rest or who have been hospitalized.  The treatment is with topical steroid creams.  Unlike many of the other skin blistering diseases, Grover’s disease has a very good prognosis.