Panniculitis – Overview

January 1st, 2013

Panniculitis, otherwise known as inflammation of the subcutaneous tissue, which is the third layer of the skin and commonly referred to as the fat layer, has many different etiologies.  However, most types of panniculitis present with a similar clinical appearance of an indurated, tender nodule in the skin.  Typically, a skin biopsy is needed to delineate the etiology of the panniculitis and a broad classification can usually be made into a septal or lobular panniculitis. In a septal panniculitis, the inflammation is concentrated around the interstitium of the fat lobules.  Whereas in a lobular panniculitis, the inflammation involves the actual fat lobules

Panniculitis