Panniculitis – Sclerosing Lipogranuloma

March 9th, 2013

Sclerosing Lipogranuloma is a type of panniculitis that I encounter in both my The Woodlands dermatology and Conroe dermatology offices due to a granulomatous reaction to a foreign body implanted in the skin.  Typically, the foreign body is injected for cosmetic purposes such as silicone or mineral oil.  The formation of a Sclerosing Lipogranuloma may occur within a few months of the injection or years later.  Clinically, the skin becomes hyperpigmented and erythematous (red) and extremely indurated (thick) where it cannot be pinched.  Occasionally, the foreign material is taken by the lymphatic system to the lungs or spleen resulting in end organ damage.  Treatment is limited but in small localized areas surgical excision may be indicated.

Sclerosing Lipogranuloma Histology