Squamous Cell Cancer – Multiple Keratoacanthomas

January 15th, 2011

Multiple Keratoacanthomas, also called Ferguson-Smith Type of Multiple Self-Healing Keratoacanthomas, are identical clinically and histologically with the Solitary Keratoacanthoma type and I occasionally encounter the Multiple Keratoacanthomas in my The Woodlands dermatology and Conroe dermatology offices.  Multiple Keratoacanthomas are usually hereditary and originated in two large Scottish families.  Patients begin developing Multiple Keratoacanthomas in their 20’s and usually three to ten Keratocacanthomas arise at once.  Sun exposed areas such as the face, neck, and arms are the most common sites affected.  Additionally, patients with Multiple Keratoacanthomas can develop the lesions at sites of trauma.  The Keratoacanthomas typically involute leaving a depressed scar, but early treatment with excision is usually curative and the incision scar more aesthetically pleasing.