Neutrophilic IgA Dermatosis is a rare blistering disease of the skin that I occasionally encounter in both my The Woodlands dermatology and Conroe dermatology offices. Clinically, the blisters are very fragile and rupture quickly forming a crust or scab. Typically, the oral mucosa is not involved. Within the blisters pus is usually found since the inflammatory cell involved in this disease is the neutrophil which is responsible for the production of purulent discharge. Unlike other blistering skin diseases, the autoimmune antibody is IgA and not IgG. Treatment is with immunosuppressive medicines.
October 6, 2012
Medically reviewed by Anthony J. Perri, M.D.
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