Histiocytoses – Progressive Nodular Histiocytosis

Progressive Nodular Histiocytosis is a type of Non-X Histiocytosis that I occasionally encounter in both my The Woodlands dermatology and Conroe dermatology offices.  Clinically, a patient develops a nodule that has a superficial portion near the surface of the skin and a deeper portion that can extend into the fat layer of the skin.  Multiple lesions can develop and are usually symmetrical.  In most patients, Progressive Nodular Histiocytosis is limited to the skin with no internal involvement.