Sea Blue Histiocytosis is a type of histiocytosis that is very rarely encountered in both my The Woodlands dermatology and Conroe dermatology offices. It is both an inherited disease and an acquired disease that can arise sporadically. The hallmark of Sea Blue Histiocytosis is a histiocyte cell that stains bluish green using a Giemsa stain. Clinically, the histiocytes can infiltrate the skin, spleen, bone marrow, lymph nodes and lungs. The cutaneous manifestations appear as skin colored papules and grey pigmentation on the upper body. Occasionally, eyelid swelling can be observed.
