Seborrheic Keratosis – Warty Dyskeratoma

February 6th, 2011

Warty Dyskeratomas are solitary lesions that can mimic the appearance of Seborrheic Keratoses and I frequently encounter them in both my The Woodlands dermatology and Conroe dermatology offices.  Warty Dyskeratomas are found on the head and neck in 70% of cases but can also occur on the trunk and extremities.  Warty Dyskeratomas are scaly nodules with a central keratotic plug that can also resemble squamous cell cancer so they are usually biopsied.  On histology, features of Darier’s Disease can be seen but the clinical picture differentiates Warty Dyskeratoma as it is a solitary nodule and not multiple crusted papules as seen in Darier’s Disease.  Treatment of Warty Dyskeratoma is either through liquid nitrogen destruction or shave excision removal.

Warty Dyskeratoma Histology